The ovaries’ failure to produce estrogen is directly related to vaginal atrophy onset, due to the particular sensitivity of the genital tract to the decreased levels of estrogen1, 12. Vaginal atrophy symptoms usually appear 4-5 years after menopause and can affect up to 50% of women 1 at this stage of their lives. In contrast to menopausal symptoms, which are usually transient, vaginal atrophy can worsen over the years with negative consequences on sexuality13 and quality of life; however, despite this, only 25% of patients decide to seek medical attention, which often leads to an underestimation of the disorder… Download document